Information fusion techniques are at high interest with the increase in dimensionality of the data being handled. They are applied in different applications, such as in the biomedical domain. This paper proposes an information fusion model that predicts the occurrence of ARDS using vital signs. This model uses features fusion based on the belief functions theory. Different linear and nonlinear parameters are first extracted from the signals, and a parameters selection procedure is proposed to select only pertinent parameters. These parameters are then used to construct mass functions in the belief functions framework. Afterwards, the prediction is performed in real-time by combining all the constructed mass functions. Results present the effectiveness of the belief theory predicting ARDS using the MIMIC II public database. Index Terms-acute respiratory distress syndrome, belief functions theory, features fusion, linear and non-linear parameters